BCAA
Have you ever wondered what BCAAs are and why they are so popular among athletes? If so, this article is for you. Here you will learn what BCAAs are, how to use them, what effects you can expect and whether they have any side effects.

What are BCAAs?
BCAA is an abbreviation for branched-chain amino acids, i.e. branched amino acids. These are three exogenous amino acids, i.e. those that the body cannot produce itself and must obtain them from food or supplements. These are leucine, isoleucine and valine. These three amino acids constitute almost half of the essential amino acids in the diet and over one third of the amino acids found in skeletal muscle. In addition, amino acids also form peptides.
BCAA – functions in the body
Branched chain amino acids have many important functions in the body. Firstly, are involved in the synthesis of muscle proteins, i.e. the process of building new muscle fibers. Leucine is particularly important in this aspect because it stimulates the so-called mTOR pathway, which is crucial for muscle anabolism. Secondly, inhibit muscle catabolism, i.e. the breakdown of muscle proteins into amino acids. This is because amino acids are used as an energy source by muscles during exercise and reduce the need for glucose.
Third, BCAAs influence glucose and insulin metabolism. Isoleucine increases glucose uptake by muscle cells and improves their insulin sensitivity, which helps maintain stable blood sugar levels and prevents fat accumulation. Fourth, amino acids may have a beneficial effect on the nervous and immune systems. BCAAs are precursors to neurotransmitters such as serotonin and glutamate, which regulate mood, sleep and appetite. In addition, they can support the synthesis of glutathione, which is a strong antioxidant and protects cells against damage.
So, as you can see, BCAAs have many benefits for health and fitness. Therefore, they are often used as dietary supplements by people practicing strength, endurance or mixed sports. Amino acid supplementation can help increase muscle mass and strength, improve post-workout recovery, reduce fatigue and soreness, and prevent muscle loss while reducing body fat.
How to dose BCAA?
There is no one universal answer to this question, because the dosage and duration of taking the supplement depend on many factors, such as the type of physical activity, training goal, diet or individual tolerance. However, some general rules can be given:
- The recommended daily dose is from 10 to 20 g per day.
- The best ratio of leucine to isoleucine and valine is 2:1:1 or 4:1:1, because leucine is the most anabolic amino acid of this group.
- BCAAs can be taken before, during or after training, depending on your preference and goal. Taking amino acids before training can provide your muscles with a source of energy and prevent catabolism. BCAA during training can delay fatigue and improve performance. Taking amino acids after training can accelerate the regeneration and synthesis of muscle proteins.
- BCAA can be combined with other supplements, such as creatine, beta-alanine, citrulline or caffeine, to increase their effectiveness and synergism.
- Amino acids are best dissolved in water or another non-alcoholic drink and drunk in small portions throughout the day.
Do branched chain amino acids have side effects?
Amino acids are considered safe and well tolerated by most people. However, some side effects may occur, such as:
- Nausea, abdominal pain, diarrhea or constipation. They may be caused by an excess of BCAAs or a low-quality supplement. In this case, the dose should be reduced or the product should be changed.
- Sleep disturbances, irritability, anxiety or depression. They may be caused by the effect of BCAAs on the synthesis of serotonin and other neurotransmitters. In this case, you should avoid taking BCAA in the evening or before bed.
- Nitrogen disorders, metabolic acidosis, or liver or kidney damage. They may be caused by excessive BCAA supplementation or metabolic disorders. In this case, you should consult a doctor and monitor the levels of ammonia, urea and creatinine in the blood.
Summary
To sum up, BCAA are dietary supplements that can bring many benefits to physically active people. However, you should remember about the appropriate dosage, time of intake and quality of the product. In addition, you should pay attention to possible side effects and the body’s reactions to supplementation.
Sources: